PFPE-PEG-PFPE is triblock copolymer with one central PEG block and two PFPE blocks on both ends. PFPE (perfluoro polyether), Krytox, is a perfluorocarbon polymer and its conjugation to PEG is through stable amide bonds. The unique surfactant is ideal for dispersion between fluorocarbon oil phase and aqueous phase. The fluorocarbon PEG block copolymer is useful in preparing perfluoronated surfactants and oil droplets in droplet microfluidics for single cell analysis, flow cytometry, droplet based assays. The compatibility of this emulsion system with both biological systems and polydimethylsiloxane (PDMS) microfluidic devices makes these surfactants ideal for a broad range of high-throughput, drop-based applications.
Alternatively, Jeffamine may replace PEG to prepare Jeffamine-PFPE surfactants. Jeffamine® is a registered trademark of Huntsman for polyetheramine. They are a range of monoamine, diamine and triamine attached to a polyether backbone typically based on ethylene oxide (PEO), propylene oxide (PPO) or a mix of both.